Stem cell-based approach to identify regulatory TFs during mammalian cell differentiation
This work is the first comprehensive characterization of all transcription factors required for a specific lineage differentiation with stage-by-stage resolution. It revealed the separation of TF networks regulating general and lineage-specific differentiation across different mammalian species.
This work is the first comprehensive characterization of all transcription factors required for a specific lineage differentiation with stage-by-stage resolution. It revealed the separation of TF networks regulating general and lineage-specific differentiation across different mammalian species.
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